Every developer has a list of tools and tweaks that they build up over time to increase their productivity. Here is a list of the little things I find useful to install everytime I set up a new machine. For reference, I am running Mac OS X 10.8 Mountain Lion, so many of these tools may be specific to that platform.
See my osx.sh for a list of useful Terminal hacks.
See these articles to set up your own awesome keyboard mappings.
In addition, modify Application windows in System Preferences -> Keyboard -> Keyboard Shortcuts -> Mission Control to respond to
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LESSvia Package Control (GitHub)
CoffeeScriptvia Package Control (GitHub)
jQueryvia Package Control (GitHub)
Gitvia Package Control (GitHub)
Tagvia Package Control (GitHub)